基本情况:

民族：汉  

出生年月：1988年11月

常用邮箱：xu.zhu.nju@gmail.com

教育及工作经历：

2016.10-至今         诺华制药               临床药理       研究员

2010.09-2016.09      纽约州立大学水牛城分校   药学          博士

2006.09-2010.06       南京大学               生物学         学士

发表论文情况:

1. Chaudhury A, Zhu X, Chu L, Goliaei A, June CH, Kearns JD, Stein AM (2020) Chimeric Antigen Receptor T-Cell (CART) Therapies: A Review of Cellular Kinetic-Pharmacodynamic Modeling Approaches, J Clin. Pharmacol.; 60 Suppl 1:S147-S159.

2. Zhu X, Trueman S, Straubinger RM, Jusko WJ (2018) Physiologically-based pharmacokinetic and pharmacodynamic models for gemcitabine and birinapant in pancreatic cancer xenografts, J Pharmacokinet Pharmacodyn; 45(5):733-746.

3. Zhu X, Shen X, Qu J, Straubinger RM, Jusko WJ (2018) Multi-scale network model supported by proteomics for analysis of combined gemcitabine and birinapant effects in pancreatic cancer cells, CPT Pharmacometrics Syst Pharmacol; 7(9):549-561.

4. Zhu X, Shen X, Qu J, Straubinger RM, Jusko WJ (2018) Proteomic analysis of combined gemcitabine and birinapant in pancreatic cancer cells, Front Pharmacol; 9:84.

5. Zhu X, Straubinger RM, Jusko WJ (2015) Mechanism-based mathematical modeling of combined gemcitabine and birinapant in pancreatic cancer cells, J Pharmacokinet Pharmacodyn; 42(5):477-96.

6. Zhao W, Zhang T, Qu B, Wu X, Zhu X, Meng F, Gu Y, Shu Y, Shen Y, Sun Y, Xu Q (2011) Sorafenib induces apoptosis in HL60 cells by inhibiting Src kinase-mediated STAT3 phosphorylation, Anticancer Drugs; 22(1):79-88.

7. Gu YH, Zhao W, Meng FY, Qu BQ, Zhu X, Sun Y, and Xu Q (2010) Sunitinib impairs the proliferation and function of human peripheral T-cell and prevents T-cell mediated immune response in mice, Clin Immunol; 135(1):55-62.

获奖情况：

· AAPS Graduate Student Research Awards in Pharmacokinetics, Pharmacodynamics, Drug Metabolism and Clinical Pharmacology and Translational Research. AAPS Annual Meeting and Exposition, Orlando, FL, 2015 Oct.