基本情况:

民族：汉  

出生年月：1979年8月

常用邮箱：njuguo@njucm.edu.cn

教育及工作经历：

2018.08--至今         南京中医药大学          中药学          教授

2012.08-2018.07           南京中医药大学          中药学          副研究员

2007.09-2012.07           南京中医药大学          中药学          助理研究员

2004.09-2007.06       南京大学                生理学          博士

2001.09-2004.06       中国药科大学大学        中西医结合      硕士

1997.09-2001.06       山东大学                药学            学士

发表论文情况:

[1] Yingyi Wang, Jianping Li, Chenkai Chen, Jingbo Lu, Jingao Yu, Xuejun Xu, Yin Peng, Sen Zhang, Shu Jiang, Jianming Guo* and Jinao Duan*. Targeting the gut microbial metabolic pathway with small molecules decreases uremic toxin production. Gut Microbes. 2020 Volume 12 Issue 1 1-19 *共同通讯作者

[2] 李成曦;王颖异;李建萍;王雨萌;张森;段金廒;郭建明*.靶向肠道细菌呼吸及能量代谢遏制炎症性肠病进展的治疗策略分析.药学学报2020；55(9): 2008-2018 *通讯作者

[3] 陆静波，王颖异，张森，李建萍，李成曦，徐雪君，彭印，陈晨凯，郭建明*，段金廒*，黄葵四物方调控肠道菌群中代谢通路干预尿毒素合成的作用机制研究，药学学报2020；55（6）：1229-1236 *共同通讯作者

[4] Yu JG, Yang Liu, Guo JM*, Tao W, Yanyan Chen, Xiuhe Fan, Juan Shen,Jin-ao Duan*. Health risk of Licorice-Yuanhua combination through induction of colonic H2S metabolism. J Ethnopharmacol. 2019, 236, 23:136-146. *共同通讯作者

[5] Jianping Li1, Yingyi Wang1, Xuejun Xu, Wenjuan Cao, Zhiqiang Shen, Nan Wang, Jing Lengc, Ning Zou, ErXin Shang, Zhenhua Zhu, Jianming Guo*, Jinao Duan*. Improved dialysis removal of protein-bound uremic toxins by salvianolic acids. Phytomedicine 2019 57: 166–173 *共同通讯作者

[6] 王颖异，李建萍，陆静波，李成曦，于金高，张森，江曙，郭建明*，段金廒* 黄葵减轻慢性肾病模型大鼠体内尿毒素蓄积的作用及机制研究。药学学报 2019; 54(12): 2267-2276 *共同通讯作者

[7] Yu JG, Guo JM*, Tao W*, Liu P, Shang EX, Chen Y, Hua Y, Zhu KY, Tang Y, Duan JA*. Gancao-Gansui combination impacts gut microbiota diversity and related metabolic functions. J Ethnopharmacol. 2018, 214, 71-82. *共同通讯作者  

[8] Yang Liu, Li JP, Yu JG, Yingyi Wang, Jingbo Lu, Er-Xin Shang, Zhenhua Zhu, Guo JM*, Duan JA*. Disorder of gut amino acids metabolism during CKD progression is related with gut microbiota dysbiosis and metagenome change. J Pharm Biomed Anal. 2018, 149: 425-435. *共同通讯作者  

[9] Yu JG, Guo JM*, Zhu KY*, Tao W, Chen Y, Liu P, Hua Y, Tang Y, Duan JA*. How impaired efficacy happened between Gancao and Yuanhua: Compounds, targets and pathways. Sci Rep. 2017 Jun 19;7(1):3828. *共同通讯作者

[10] Li JP, Guo JM*, Shang EX, Zhu ZH, Liu Y, Zhao BC, Zhao J, Tang ZS, Duan JA*. Quantitative determination of five metabolites of aspirin by UHPLC-MS/MS coupled with enzymatic reaction and its application to evaluate the effects of aspirin dosage on the metabolic profile. J Pharm Biomed Anal. 2017 May 10;138:109-117*共同通讯作者

[11] Li JP, Guo JM*, Shang E, Zhu Z, Zhu KY, Li S, Zhao B, Jia L, Zhao J, Tang Z, Duan JA*.A metabolomics strategy to explore urinary biomarkers and metabolic pathways for assessment of interaction between Danhong injection and low-dose aspirin during their synergistic treatment. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Jul 15;1026:168-75.*共同通讯作者

[12] Li JP#, Guo JM#, Hua YQ, Zhu KY, Tang YP, Zhao BC, Jia LF, Zhao J, Tang ZS, Duan JA*. The mixture of Salvia miltiorrhiza-Carthamus tinctorius (Danhong injection) alleviates low-dose aspirin induced gastric mucosal damage in rats. Phytomedicine. 2016 Jun 1;23(6):662-71. #并列第一作者

[13] Guo JM, Du L, Shang E, Li T, Liu Y, Qian D, Tang Y, Duan J*. Conjugated metabolites represent the major circulating forms of Abelmoschus manihot in vivo and show an altered pharmacokinetic profile in renal pathology. Pharm Biol. 2016;54(4):595-603. 第一作者

获奖情况：

1. 获得2013年度中华中医药学会科学技术奖一等奖（排名第8）

2. 获得2014年度教育部高等学校自然科学奖一等奖（排名第11）