基本情况:

民族：侗族  

出生年月：1989年12月

常用邮箱：ouyangzijun@szpt.edu.cn

教育及工作经历：

2020.01--至今      深圳职业技术学院                药学专业           讲师

2018.10-2019.12    广东科贸职业学院                药品生物技术专业   讲师2017.07-2017.12    中国科学院深圳先进技术研究院    脑所               助理研究员                  2012.09-2017.06    南京大学                        药学               博士

2008.09-2012.06    中国药科大学                    中药资源与开发     学士

发表论文情况:

1.Zhan T, Wang X, Ouyang Z, Yao Y, Xu J, Liu S, Liu K, Deng Q, Wang Y, Zhao Y. Rotating magnetic field ameliorates experimental autoimmune encephalomyelitis by promoting T cell peripheral accumulation and regulating the balance of Treg and Th1/Th17. AGING. 2020, 12.

2.Xu J, Liu K, Chen T, Zhan T, Ouyang Z, Wang Y, Liu W, Zhang X, Sun Y, Xu G, Wang X. Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans. AGING 2019, 11.

3.Zhao M #, Shen L#, Ouyang Z #, Li M, Deng G, Yang C, Zheng W, Kong L, Wu X, Wu X, Guo W, Yin Y*, Xu Q*, Sun Y*. Loss of hnRNP A1 in murine skeletal muscle exacerbates high fat diet-induced onset of insulin resistance and hepatic steatosis. Journal of Molecular Cell Biology. 2019, 10, 1093.

4.Ouyang Z, Li W, Meng Q, et al. A natural compound jaceosidin ameliorates endoplasmic reticulum stress and insulin resistance via upregulation of SERCA2b. Biomed Pharmacother. 2017.

5.Ouyang Z, Wang X, Meng Q, et al. Suppression of adenosine monophosphate-activated protein kinase selectively triggers apoptosis in activated T cells and ameliorates immune diseases. Biochem Biophys Res Commun. 2017.

6.Li W#, Ouyang Z#, Zhang Q, et al. SBF-1 exerts strong anticervical cancer effect through inducing endoplasmic reticulum stress-associated cell death via targeting sarco/endoplasmic reticulum Ca(2+)-ATPase 2. Cell Death Dis. 2014. 

7.Wu X, Ouyang Z, Feng L, et al. Suppression of NF-kappaB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone. Toxicol Appl Pharmacol. 2014.

8.Wang X, Ouyang Z, You Q, et al. Obaculactone protects against bleomycin-induced pulmonary fibrosis in mice. Toxicol Appl Pharmacol. 2016.

9.Wang X, Zhou Y, He S, Ouyang Z, Feng F, Shen Y, Wu X, Sun Y, W X*, Xu Q*. Obaculactone exerts a novel ameliorating effect on contact dermatitis through regulating T lymphocyte. International Immunopharmacology. 2015, 28(1), 1-9

10.Wu X, Fan J, Ouyang Z, et al. Tupistra chinensis extract attenuates murine fulminant hepatitis with multiple targets against activated T lymphocytes. J Pharm Pharmacol. 2014.

11.Li W, Yang Y, Ouyang Z, et al. Xiao-Ai-Ping, a TCM Injection, Enhances the Antigrowth Effects of Cisplatin on Lewis Lung Cancer Cells through Promoting the Infiltration and Function of CD8(+) T Lymphocytes. Evid Based Complement Alternat Med. 2013.

12.Wu X, Xu R, Ouyang Z, et al. Beauvericin ameliorates experimental colitis by inhibiting activated T cells via downregulation of the PI3K/Akt signaling pathway. PLoS One. 2013.

主持项目情况：

1. 国家自然科学基金青年基金，81803081，基于肿瘤干细胞标志物的T7-多糖-多肽“三明治”式多靶点疫苗的抗肿瘤效应与机制研究，2019/01-2021/12，在研，主持；

2. 广东省教育厅普通高校特色创新项目，2019GKTSCX039，基于胰岛素信号转导通路探索棕矢车菊素治疗2型糖尿病的机制研究，2020/01-2022/12，在研，主持；

3. 广东省组织器官区域免疫与疾病重点实验室开放基金，2019B030301009-007，组学联合分析筛选坏死性小肠结肠炎生物标志物，2020/07-2021/12，在研，主持；