基本情况：

民族：汉

出生年月：1992年8月

常用邮箱：dz1630014@smail.nju.edu.cn

教育及工作经历：

2016.09-至今 南京大学 药学 博士

2012.09-2016.06 南京师范大学 生物技术 学士

发表论文情况：

1. Yuyu Zhu^#, Ning Wan^#, Xinni Shan, Guoliang Deng, Qiang Xu, Hui Ye*, Yang Sun*. Celastrol targets adenylyl cyclase-associated protein 1 to reduce macrophages-mediated inflammation and ameliorates high fat diet-induced metabolic syndrome in mice[J]. Acta Pharmaceutica Sinica B, 10.1016/j.apsb.2020.12.008.

2. Wen Liu^#, Meijing Wang^#, Lihong Shen^#, Yuyu Zhu, Hongyue Ma, Bo Liu, Liang Ouyang, Wenjie Guo*, Qiang Xu*, Yang Sun*. SHP2-mediated mitophagy boosted by lovastatin in neuronal cells alleviates parkinsonism in mice[J]. Signal Transduction and Targeted Therapy, 10.1038/s41392-021-00474-x.

3. Yuyu Zhu, Chenglin Song, Yang Sun*. Advances in mechanisms for psoriasis and drug regulation[J]. Acta Pharmaceutica Sinica, 55,1393-1400(2020).

4. Wen Liu^#, Ye Yin^#, Meijing Wang^#, Ting Fan, Yuyu Zhu, Lihong Shen, Shuang Peng, Jian Gao, Guoliang Deng, Xiangbao Meng, Lingdong Kong, Gen-Sheng Feng, Wenjie Guo*, Qiang Xu*, Yang Sun*. Disrupting phosphatase SHP2 in macrophages protects mice from high-fat diet-induced hepatic steatosis and insulin resistance by elevating IL-18 levels[J]. Journal of Biological Chemistry, 295, 10842-10856(2020).

5. Mingxia Zhao^#, Wenjie Guo^#, Yuanyuan Wu^#, Chenxi yang, Liang Zhong, Guoliang Deng, Yuyu Zhu, Wen Liu, Yanhong Gu, Yin Lu, Lingdong Kong, Xiangbao Meng*, Qiang Xu*, Yang Sun*. SHP2 inhibition triggers anti-tumor immunity and synergizes with PD-1 blockade[J]. Acta Pharmaceutica Sinica B, 2,304-315(2018).

6. Wen Liu^#, Wenjie Guo^#, Yongcheng Zhu, Shuang Peng, Wei Zheng, Chao Zhang, Fenli Shao, Yuyu Zhu, Nan Hang, Lingdong Kong, Xiangbao Meng, Qiang Xu*, Yang Sun*. Targeting Peroxiredoxin 1 by a Curcumin Analogue, AI-44, Inhibits NLRP3 Inflammasome Activation and Attenuates Lipopolysaccharide-Induced Sepsis in Mice[J]. The Journal of Immunology, 8,2403-2413(2018).

7. Xiao Li, Yajie Zhang, Jian Sun, Weijian Chen, Xuewei Wang, Fenli Shao, Yuyu Zhu, Fude Feng*, Yang Sun*. Protein Nanocage-Based Photo-Controlled Nitric Oxide Releasing Platform[J]. ACS Applied Materials & Interfaces, 23,19519-19524(2017).