Molpharm实验室2016年度发表文章情况:
1. XX Wu, XD Wu*, Y Ma, F Shao, Y Tan, T Tan, L Gu, Y Zhou, B Sun, Y Sun, XF Wu*, Q Xu*. CUG-binding protein 1 regulates HSC activation and liver fibrogenesis. Nat Commun 2016; 7: 13498.
2. X Wang, X Wu, A Zhang, S Wang, C Hu, W Chen, Y Shen, R Tan*, Y Sun*, Q Xu*. Targeting the PDGF-B/PDGFR-β interface with destruxin A5 to selectively block PDGF-BB/PDGFR-ββ signaling and attenuate liver fibrosis. EBioMedicine 2016, 7: 146-156.
3. Y Tan, X Wu, J Sun, W Guo, F Gong, F Shao, T Tan, Y Cao, B Zheng, Y Gu, Y Sun*, Q Xu*. A fumigaclavine C isostere alleviates Th1-mediated experimental colitis via competing with IFN-γ for binding to IFN-γ receptor 1. Biochem Pharmacol 2016, doi: 10.1016/j.bcp.2016.10.004.
4. A Elgehama, W Chen, J Pang, S Mi, J Li, W Guo, X Wang, J Gao, B Yu, Y Shen*, Q Xu*. Blockade of the interaction between Bcr-Abl and ptb1b by small molecule SBF-1 to overcome imatinib-resistance of chronic myeloid leukemia cells. Cancer Lett 2016;372(1):82-8.
5. X Wang, C Hu, X Wu, S Wang, A Zhang, W Chen, Y Shen, R Tan, X Wu, Y Sun, Q Xu*. Roseotoxin B improves allergic contact dermatitis through a unique anti-inflammatory mechanism involving excessive activation of autophagy in activated T lymphocytes. J Invest Dermatol 2016;136(8):1636-46.
6. F Shao, T Tan, T Yang, Y Sun, XX Wu*, Q Xu*. Andrographolide alleviates imiquimod-induced psoriasis in mice via inducing autophagic proteolysis of myd88. Biochem Pharmacol 2016;115:94-103.
7. W Liu, W Guo, L Shen, Z Chen, Q Luo, X Luo, GS Feng, Y Shu, Y Gu*, Q Xu*, Y Sun*. T lymphocyte SHP2-deficiency triggers anti-tumor immunity to inhibit colitis-associated cancer in mice. Oncotarget 2016, doi: 10.18632/oncotarget.13812
8. S Peng, N Hang, W Liu, W Guo, C Jiang, X Yang, Q Xu*, Y Sun*. Andrographolide sulfonate ameliorates LPS-induced acute lung injury in mice through down-regulating MAPK and NF-κB pathways. Acta Pharmaceutica Sinica B, 2016, 6(3):205-211.
9. X Wang, Z Ouyang, Q You, S He, Q Meng, C Hu, X Wu, Y Shen, Y Sun*, XF Wu*, Q Xu*. Obaculactone protects against bleomycin-induced pulmonary fibrosis in mice. Toxicol Appl Pharmacol 2016;303:21-9.
10. S Mi, G Xiang, D Yuwen, J Gao, W Guo, X Wu, X Wu, Y Sun, Y Su, Y Shen*, Q Xu*. Inhibition of autophagy by andrographolide resensitizes cisplatin-resistant non-small cell lung carcinoma cells via activation of the Akt/mTOR pathway. Toxicol Appl Pharmacol 2016;310:78-86.
11. X Li, X Wang, H Jiang, G Zhang, R Tan, Y Sun, X Wu, R Tan*, Q Xu*. Herpetol ameliorates allergic contact dermatitis through regulating T-lymphocytes. Int Immunopharmacol 2016;40:131-138.
12. G Xu, LL Feng, PP Song, F Xu, A Li, Y Wang, Y Shen, XF Wu, Q Luo, XX Wu, Y Sun, XD Wu*, Q Xu*. Isomeranzin suppresses inflammation by inhibiting M1 macrophage polarization through the NF-κB and ERK pathway. Int Immunopharmacol 2016;38:175-185.
 

 

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