1. Mingjian Fei, Xuefeng Wu, Qiang Xu. Astilbin Inhibits Contact hypersensitivity via Negative Cytokine Regulation Distinct from Cyclosporin A. J Allergy Clin Immunol. 2005; 116(6): 1350-1356.

Highlight: IL-10 is known as a negative regulator for inflammatory diseases, including contact dermatitis. However, only a few drug candidates are reported to induce endogenous IL-10. This study reported that astilbin alleviated contact hypersensitivity through a unique mechanism involving a negative cytokine regulation through stimulating IL-10, which is distinct from the immunosuppressant cyclosporin A.

2. Xinhui Tang, Jing Gao, Jin Chen, Feng Fang, Yanping Wang, Huan Dou, Qiang Xu, Zhongming Qian. Inhibition of Ursolic acid on calcium-induced mitochondrial permeability transition and release of two proapoptotic proteins. Biochem Biophy Res Comm 2005; 337: 320-324.
3. Feng Qian, Zi-Chao Zhang, Xue-Feng Wu, Yu-Pei Li, Qiang Xu. Interaction between integrin a5 and fibronectin is required for metastasis of B16F10 melanoma cells. Biochem. Biophy. Res. Comm.2005, 333: 1269-1275.
4. Ling Xu, Ying Zhao, Yu Qin, Qiang Xu. A Novel Model of Acute Liver Injury in Mice Induced by T Cell-Mediated Immune Response to Lactosylated Bovine Serum Albumin. Clin. Exp. Immunol. 2006; 144: 125-133. 
5. Ying Shao, Junyong Zhang, Chao Tu, Chunhui Dai, Qiang Xu, Zijian Guo. Steric effect on the nuclease activity of Cu(II) complexes with aminoquinoline derivatives. J. Inorg. Biochem. 2005; 99: 1490-1496.
6. Xianming Zhang, Jia Chen, Yugui Xia, Qiang Xu. Apoptosis of murine melanoma B16-BL6 cells induced by quercetin targeting mitochondria, inhibiting expression of PKC-a  and translocating PKC-d.Cancer Chemother Pharmacol 2005; 55: 251-262.
7. Sun Y, Xu Q. Ethanol extract from Artemisia vestita, a traditional Tibetan medicine, exerts anti-sepsis action through down-regulating
the MAPK and NF-kappaB pathways. Int J Mol Med. 2006; 17(5): 957-62.
8. Jule Wang, Yang Sun, Yihua Li and Qiang Xu. Aqueous extract from aerial parts of Artemisia vestita, a traditional Tibetan medicine, reduces contact sensitivity in mice by down-regulating the activation, adhesion and metalloproteinase production of T lymphocytes. Int. Immunopharmacol. 2005, 5: 407-415.
9. Li Zhang, Yang Sun, Ting Chen, Qiang Xu. Selective depletion of glycyrrhizin from Si-Ni-San, a traditional Chinese prescription, blocks its effect on contact sensitivity in mice and recovers adhesion and metalloproteinases production of T lymphocytes. Int. Immunopharmacol. 2005, 5: 1193-1204.
10. Xuefeng Wu, Mingjian Fei, Rengeng Shu, Renxiang Tan, Qiang Xu. Fumigaclavine C, an fungal metabolite, improves experimental colitis in mice via downregulating Th1 cytokine production and metrix metalloproteinase activity. Int. Immunopharmacol. 2005, 5: 1543-1553.
11.  Junping Kou, Yang Sun,Yuwen Lin, Zhihong Cheng, Wei Zheng, Boyang Yu, and Qiang Xu. Anti-inflammatory Activities of Aqueous Extract from Radix Ophiopogonjaponicus and Its Two Constituents. Biol. Pharm. Bull.,2005; 28(7): 1234-1238.
12. Junping Kou, Boyang Yu, Qiang Xu. Inhibitory effects of ethanol extract from Radix Ophiopogonjaponicus on venous thrombosis linked with its endothelium-protective and anti-adhesive activities. Vascular Pharmacology, 2005; 43 (3): 157-163.
13. Xin-hui Tang, Jing Gao, Yan-Ping Wang, Yi-Mei Fan, Li-ZhiXu, Huan Dou, Qiang Xu. Hepatoprotection of Oleanolic Acid is Related to its Inhibition on Mitochondrial Permeability Transition. Am. J. Chin. Med. 2005; 33 (4) : 627-637.


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